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Ytterbium‐Based Bioprobes for Near‐Infrared Two‐Photon Scanning Laser Microscopy Imaging
Author(s) -
D'Aléo Anthony,
Bourdolle Adrien,
Brustlein Sophie,
Fauquier Teddy,
Grichine Alexei,
Duperray Alain,
Baldeck Patrice L.,
Andraud Chantal,
Brasselet Sophie,
Maury Olivier
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201202212
Subject(s) - ytterbium , infrared , two photon excitation microscopy , microscopy , luminescence , materials science , optics , photon , laser , microscope , optoelectronics , physics , fluorescence
Cleanly separated by two photons : The design and photophysical characterization of a new highly stable macrocyclic ytterbium complex featuring a two‐photon antenna ligand is described (see picture). The biphotonic sensitization of the near‐infrared ytterbium(III) luminescence and the conception of an unconventional near‐infrared biphotonic microscope allow performing in‐depth imaging of thick tissues.

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