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Transporting Excess Electrons along Potential Energy Gradients Provided by 2 ′ ‐Deoxyuridine Derivatives in DNA
Author(s) -
Ito Takeo,
Hamaguchi Yuta,
Tanabe Kazuhito,
Yamada Hisatsugu,
Nishimoto Seiichi
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201202141
Subject(s) - homo/lumo , deoxyuridine , electron , dna , thymidine , chemistry , molecule , electron transport chain , photochemistry , stereochemistry , physics , organic chemistry , biochemistry , quantum mechanics
LUMO‐level dependent : Chemically modified DNA molecules containing 2 ′ ‐deoxyuridine (dU) derivatives with various LUMO energy levels have been synthesized to manipulate electron‐transfer efficiencies. By arranging thymidine, the dU derivatives, and 5‐fluoro‐2 ′ ‐deoxyuridine in order of their LUMO levels, the efficiency and the directionality of photoinduced electron transport in DNA could be regulated.

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