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Cover Picture: Trienamine Catalysis with 2,4‐Dienones: Development and Application in Asymmetric Diels–Alder Reactions (Angew. Chem. Int. Ed. 18/2012)
Author(s) -
Xiong XiaoFeng,
Zhou Quan,
Gu Jing,
Dong Lin,
Liu TianYu,
Chen YingChun
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201202102
Subject(s) - cyclohexene , chemistry , cycloaddition , nitrosobenzene , catalysis , stereochemistry , adduct , organic chemistry
An asymmetric Diels‐Alder cycloaddition of δ,δ‐disubstituted 2,4‐dienones by trienamine catalysis with cinchona‐based primary amines has been developed. In their Communication on page 4401 ff. , Y.‐C. Chen and co‐workers show that a wide range of electron‐deficient dienophiles were tolerated in this reaction to afford multifunctional cyclohexene derivatives with excellent stereoselectivity.