Premium
Degree of Chemical Functionalization of Carbon Nanotubes Determines Tissue Distribution and Excretion Profile
Author(s) -
AlJamal Khuloud T.,
Nunes Antonio,
Methven Laura,
AliBoucetta Hanene,
Li Shouping,
Toma Francesca M.,
Herrero M. Antonia,
AlJamal Wafa' T.,
ten Eikelder Huub M. M.,
Foster Julie,
Mather Stephen,
Prato Maurizio,
Bianco Alberto,
Kostarelos Kostas
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201991
Subject(s) - surface modification , carbon nanotube , materials science , nanotechnology , chemical modification , carbon fibers , chemical engineering , biomedical engineering , chemistry , biophysics , polymer chemistry , composite material , medicine , biology , composite number , engineering
Getting rid of the tubes : An assessment of the retention of functionalized multi‐walled carbon nanotubes (MWNTs) in the organs of mice was carried out using single photon emission computed tomography and quantitative scintigraphy (see scheme). Increasing the degree of functionalization on MWNTs enhanced renal clearance, while lower functionalization promoted reticuloendethelial system accumulation.