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Asymmetric Epoxidation of Conjugated Olefins with Dioxygen
Author(s) -
Koya Shota,
Nishioka Yota,
Mizoguchi Hirotaka,
Uchida Tatsuya,
Katsuki Tsutomu
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201848
Subject(s) - conjugated system , ruthenium , catalysis , chemistry , molecular oxygen , oxygen , photochemistry , organic chemistry , combinatorial chemistry , polymer
A complex situation : Asymmetric epoxidation of conjugated olefins was achieved at room temperature using ruthenium complex 1 as the catalyst and air as the oxidant to give epoxides in up to 95 % ee (see scheme). When the product was acid sensitive, the reaction was carried out at 0 °C under oxygen.
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