Premium
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
Author(s) -
Yamaguchi Junichiro,
Yamaguchi Atsushi D.,
Itami Kenichiro
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201666
Subject(s) - surface modification , chemistry , combinatorial chemistry , carbon fibers , heteroatom , organic chemistry , nanotechnology , materials science , ring (chemistry) , composite number , composite material
The direct functionalization of CH bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon–carbon and carbon–heteroatom bonds. This Review provides an overview of CH bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.