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Copper‐Catalyzed Tandem CN Bond Formation: An Efficient Annulative Synthesis of Functionalized Cinnolines
Author(s) -
Ball Catherine J.,
Gilmore Jeremy,
Willis Michael C.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201529
Subject(s) - hydrazide , tandem , chemistry , combinatorial chemistry , catalysis , nucleophile , organic chemistry , materials science , composite material
Cinn‐tillating synthesis : The combination of a readily available copper catalyst, a simple hydrazide nucleophile, and established difunctionalized building blocks provides a new, flexible route to an under‐developed class of aromatic heterocycles, cinnolines (see scheme).