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Catalytic Activation of Diazo Compounds Using Electron‐Rich, Defined Iron Complexes for Carbene‐Transfer Reactions
Author(s) -
Holzwarth Michael S.,
Alt Isabel,
Plietker Bernd
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201409
Subject(s) - carbene , diazo , catalysis , reagent , chemistry , electron transfer , allylic rearrangement , photochemistry , cyclopropanation , combinatorial chemistry , medicinal chemistry , organic chemistry
Carbene transfer : The electron‐rich iron complex Bu 4 N[Fe(CO) 3 (NO)] efficiently catalyzes different carbene‐transfer reactions. Various diazo compounds can be used. The high stability of the employed iron complexes is demonstrated by the generation of the diazo reagent in situ and a sequential iron‐catalyzed allylic sulfenylation/Doyle–Kirmse reaction.