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A Rotaxane‐Based Switchable Organocatalyst
Author(s) -
Blanco Victor,
Carlone Armando,
Hänni Kevin D.,
Leigh David A.,
Lewandowski Bartosz
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201364
Subject(s) - rotaxane , cinnamaldehyde , chemistry , thiol , organocatalysis , combinatorial chemistry , nanotechnology , organic chemistry , catalysis , materials science , molecule , supramolecular chemistry , enantioselective synthesis
Switch it on! The activity of an organocatalytic group incorporated within a rotaxane architecture can be controlled by switching the position of the macrocycle. The system was used to mediate the progress of the Michael addition of an aliphatic thiol to trans ‐cinnamaldehyde.