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Knölker’s Iron Complex: An Efficient In Situ Generated Catalyst for Reductive Amination of Alkyl Aldehydes and Amines
Author(s) -
PagnouxOzherelyeva Anastassiya,
Pannetier Nicolas,
Mbaye Mbaye Diagne,
Gaillard Sylvain,
Renaud JeanLuc
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201360
Subject(s) - reductive amination , alkyl , catalysis , chemistry , amination , organic chemistry , in situ , primary (astronomy) , hydrogen , combinatorial chemistry , physics , astronomy
An aminated series : A well‐defined iron‐catalyzed reductive amination reaction of aldehydes and ketones with aliphatic amines using molecular hydrogen is presented. Under mild conditions, good yields for a broad range of alkyl ketones as well as aldehydes were achieved.