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Back Cover: Automated Solid‐Phase Synthesis of β‐Mannuronic Acid Alginates (Angew. Chem. Int. Ed. 18/2012)
Author(s) -
Walvoort Marthe T. C.,
van den Elst Hans,
Plante Obadiah J.,
Kröck Lenz,
Seeberger Peter H.,
Overkleeft Herman S.,
van der Marel Gijsbert A.,
Codée Jeroen D. C.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201338
Subject(s) - int , cover (algebra) , solid phase synthesis , chemistry , phase (matter) , polymer science , materials science , combinatorial chemistry , organic chemistry , computer science , engineering , biochemistry , mechanical engineering , peptide , operating system
The automated solid‐phase assembly of oligomannuronic acid alginates, key exopolysaccharides of the opportunistic Gram‐negative bacterium Pseudomonas aeruginosa , has been achieved through the use of mannuronic acid building blocks in a fully automated carbohydrate synthesizer. G. A. van der Marel, J. D. C. Codée, and co‐workers report in their Communication on page 4393 ff. how mannuronic acid alginate fragments with up to 12 cis‐ mannosidic linkages have been assembled by this method.