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Dual‐Responsive Boronate Crosslinked Micelles for Targeted Drug Delivery
Author(s) -
Chen Weixuan,
Cheng Yunfeng,
Wang Binghe
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201179
Subject(s) - micelle , payload (computing) , drug delivery , boronic acid , diol , nanotechnology , dual (grammatical number) , combinatorial chemistry , chemistry , drug , targeted drug delivery , computer science , materials science , organic chemistry , aqueous solution , pharmacology , computer network , medicine , art , literature , network packet
Controlled trigger finger : A novel class of micelles for targeted drug delivery was developed. The strategy relies on boronic acid–diol interactions as a way of accessing crosslinked micelles having improved stability (see scheme) and quick payload release in response to low pH environments or diol addition.