Premium
Palladium‐Catalyzed Oxidative Double CH Functionalization/Carbonylation for the Synthesis of Xanthones
Author(s) -
Zhang Hua,
Shi Renyi,
Gan Pei,
Liu Chao,
Ding Anxing,
Wang Qiuyi,
Lei Aiwen
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201050
Subject(s) - palladium , carbonylation , catalysis , surface modification , chemistry , trifluoroacetic acid , combinatorial chemistry , oxidative phosphorylation , organic synthesis , organic chemistry , carbon monoxide , biochemistry
Two at once : Xanthones with different functional groups were obtained with CO (balloon) in the presence of a simple catalytic system that consists of Pd(OAc) 2 , K 2 S 2 O 8 , and trifluoroacetic acid (see scheme). Preliminary mechanism studies reveal that the second CH functionalization might be the rate‐determining step.