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P‐Stereogenic Secondary Iminophosphorane Ligands and Their Rhodium(I) Complexes: Taking Advantage of NH/PH Tautomerism
Author(s) -
León Thierry,
Parera Magda,
Roglans Anna,
Riera Antoni,
Verdaguer Xavier
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201031
Subject(s) - tautomer , stereocenter , rhodium , chemistry , ligand (biochemistry) , sulfonyl , stereochemistry , medicinal chemistry , catalysis , organic chemistry , enantioselective synthesis , receptor , biochemistry , alkyl
Have a good SIP : P‐stereogenic secondary iminophosphorane (SIP) ligands with a sulfonyl group attached to nitrogen have been prepared. In the presence of rhodium, the tautomeric equilibrium is shifted from the favored PH tautomer towards the P III tautomer, thereby allowing coordination of the SIP ligand through the P and O atoms. The resulting Rh complexes are effective in the [2+2+2] cycloaddition of enediynes with terminal alkynes.