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Tamed Arene and Heteroarene Trifluoromethylation
Author(s) -
Besset Tatiana,
Schneider Cédric,
Cahard Dominique
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201201012
Subject(s) - trifluoromethylation , reagent , chemistry , combinatorial chemistry , organic chemistry , trifluoromethyl , alkyl
A tri‐ing transformation : The increasingly high demand for trifluoromethylated arenes and heteroarenes is a major challenge that has been addressed through the development of trifluoromethylation reactions. Several effective approaches for late‐stage trifluoromethylation, as well as the use of practical and cheap trifluoromethylation reagents, are highlighted.