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A Mild Benzannulation through Directed Cycloaddition Reactions
Author(s) -
Kirkham James D.,
Butlin Roger J.,
Harrity Joseph P. A.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201200917
Subject(s) - cycloaddition , borane , boranes , chemistry , combinatorial chemistry , substrate (aquarium) , organic chemistry , computational chemistry , catalysis , boron , biology , ecology
Simple as ABC : Alkynyl borane cycloadditions can be substrate‐directed to assemble aromatic difluoroboranes within an extremely mild and efficient reaction manifold compared to that of traditional methods (see scheme). The aromatic boranes are readily transformed into a range of useful products.