Back Cover: Enzymatically Incorporated Genomic Tags for Optical Mapping of DNA‐Binding Proteins (Angew. Chem. Int. Ed. 15/2012) | Zendy

Kim Soohong | Zendy; Gottfried Anna | Zendy; Lin Ron R. | Zendy; Dertinger Thomas | Zendy; Kim Andrew S. | Zendy; Chung Sangyoon | Zendy; Colyer Ryan A. | Zendy; Weinhold Elmar | Zendy; Weiss Shimon | Zendy; Ebenstein Yuval | Zendy

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Back Cover: Enzymatically Incorporated Genomic Tags for Optical Mapping of DNA‐Binding Proteins (Angew. Chem. Int. Ed. 15/2012)

Author(s) -

Kim Soohong,

Gottfried Anna,

Lin Ron R.,

Dertinger Thomas,

Kim Andrew S.,

Chung Sangyoon,

Colyer Ryan A.,

Weinhold Elmar,

Weiss Shimon,

Ebenstein Yuval

Publication year - 2012

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201200628

Subject(s) - dna , genomic dna , genome , cover (algebra) , computational biology , dna binding protein , biology , genetics , chemistry , microbiology and biotechnology , gene , mechanical engineering , engineering , transcription factor

The genome of the T7 bacteriophage can be mapped by using sequence‐specific methyltransferase‐induced labeling of DNA. In their Communication on page 3578 ff., E. Weinhold, S. Weiss, Y. Ebenstein, and co‐workers show that the location of RNA polymerases that are bound to DNA can be visualized as a linear optical barcode, which allows structural variations in genomic DNA to be analyzed and provides an extra layer of contextual information about the genome at the single‐molecule level.

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