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Towards a Green Process for Bulk‐Scale Synthesis of Ethyl Acetate: Efficient Acceptorless Dehydrogenation of Ethanol
Author(s) -
Nielsen Martin,
Junge Henrik,
Kammer Anja,
Beller Matthias
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201200625
Subject(s) - dehydrogenation , catalysis , ethanol , ethyl acetate , chemistry , ruthenium , process (computing) , organic chemistry , combinatorial chemistry , computer science , operating system
Green is a go : An efficient acceptorless dehydrogenative dimerization of ethanol to give ethyl acetate was realized (see scheme). The reaction proceeds under mild reaction conditions in the presence of a ruthenium catalyst with concomitant liberation of molecular hydrogen, which can be used as a valuable product itself. At low catalyst loading (50 ppm), high yields of ethyl acetate and excellent catalyst turnover numbers are achieved.