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Total Synthesis of Cyrneine A
Author(s) -
Elamparuthi Elangovan,
Fellay Cindy,
Neuburger Markus,
Gademann Karl
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201200515
Subject(s) - diterpene , computer science , sample (material) , ring (chemistry) , chemistry , stereochemistry , organic chemistry , chromatography
Neuritogenic natural products : The tricyclic diterpene cyrneine A featuring a hexatrienal unit was prepared synthetically for the first time by a Heck reaction, a carbene ring expansion, and a reductive carbonylation. The structure of the natural product was assigned by X‐ray crystal analysis of a synthetic sample.