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Electrochemical Fluorination Using Alkali‐Metal Fluorides
Author(s) -
Sawamura Takahiro,
Takahashi Kohta,
Inagi Shinsuke,
Fuchigami Toshio
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201200438
Subject(s) - fluoride , alkali metal , electrochemistry , nucleophile , solubility , ethylene glycol , inorganic chemistry , chemistry , solvent , organic chemistry , electrode , catalysis
Charged up : The selective electrochemical fluorination of organic compounds using the alkali‐metal fluoride KF under very mild reaction conditions has been accomplished (see scheme). The long‐standing problems of low solubility of metal fluorides in organic solvent and low nucleophilicity of fluoride ions for fluorination have been overcome by the use of of poly(ethylene glycol).