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Catalytic, Atom‐Economical Radical Arylation of Epoxides
Author(s) -
Gansäuer Andreas,
Behlendorf Maike,
von Laufenberg Daniel,
Fleckhaus André,
Kube Christian,
Sadasivam Dhandapani V.,
Flowers Robert A.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201200431
Subject(s) - catalysis , electron transfer , chemistry , proton , radical , atom (system on chip) , cyclic voltammetry , combinatorial chemistry , photochemistry , computer science , organic chemistry , physics , electrochemistry , electrode , quantum mechanics , embedded system
A slow electron waltz : Catalysis in single‐electron steps with radicals as intermediates is essential for an atom‐economical arylation of epoxides with a proton‐coupled electron transfer as a key step. Stabilization of the catalyst is essential for low catalyst loading, as demonstrated by reaction‐progress kinetic analysis, cyclic voltammetry, and calculations.

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