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Biomimetic Surface Engineering of Lanthanide‐Doped Upconversion Nanoparticles as Versatile Bioprobes
Author(s) -
Li LeLe,
Zhang Ruobing,
Yin Leilei,
Zheng Kezhi,
Qin Weiping,
Selvin Paul R.,
Lu Yi
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201109156
Subject(s) - nanotechnology , nanoparticle , lanthanide , photon upconversion , materials science , biomedicine , surface modification , coating , biosensor , doping , computer science , chemistry , organic chemistry , bioinformatics , biology , ion , optoelectronics
Coat of lipids : Water‐dispersible and functionalizable upconverting nanoparticles (UCNPs) for selective imaging of live cancer cells were synthesized. The synthetic approach involves coating the surface of the UCNPs with a monolayer of phospholipids that contain different functional groups (see picture), thus allowing for conjugation of many molecules for applications in fields such as bioinspired nanoassembly, biosensing, and biomedicine.