Premium
Cover Picture: In Vitro Developmental Acceleration of Hippocampal Neurons on Nanostructures of Self‐Assembled Silica Beads in Filopodium‐Size Ranges (Angew. Chem. Int. Ed. 12/2012)
Author(s) -
Kang Kyungtae,
Choi SungEun,
Jang Hee Su,
Cho Woo Kyung,
Nam Yoonkey,
Choi Insung S.,
Lee Jin Seok
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201108840
Subject(s) - cover (algebra) , monolayer , nanostructure , in vitro , nanotechnology , materials science , morphology (biology) , acceleration , biophysics , chemistry , biology , physics , biochemistry , mechanical engineering , classical mechanics , engineering , genetics
Topographical cues play an important role in in vitro neuronal development. In their Communication on page 2855 ff., Y. Nam, I. S. Choi, J. S. Lee, and co‐workers show that neuritogenetic acceleration occurs on silica‐bead monolayers made up of beads with a diameter of more than 200 nm, but not on monolayers of beads with smaller diameters. The biochemical study indicates neurons sense topographical differences in nanostructures and alter their behavior accordingly.