Inside Cover: A Synthetic Approach Toward a Self‐Regulated Insulin Delivery System (Angew. Chem. Int. Ed. 9/2012) | Zendy

Matsumoto Akira | Zendy; Ishii Takehiko | Zendy; Nishida Junko | Zendy; Matsumoto Hiroko | Zendy; Kataoka Kazunori | Zendy; Miyahara Yuji | Zendy

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Inside Cover: A Synthetic Approach Toward a Self‐Regulated Insulin Delivery System (Angew. Chem. Int. Ed. 9/2012)

Author(s) -

Matsumoto Akira,

Ishii Takehiko,

Nishida Junko,

Matsumoto Hiroko,

Kataoka Kazunori,

Miyahara Yuji

Publication year - 2012

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Reports

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201108617

Subject(s) - cover (algebra) , insulin delivery , insulin , drug delivery , derivative (finance) , int , chemistry , materials science , nanotechnology , computer science , diabetes mellitus , medicine , engineering , endocrinology , type 1 diabetes , business , operating system , mechanical engineering , finance

A totally synthetic artificial pancreas is described by Y. Miyahara et al. in their Communication on page 2124 ff . A hydrogel bearing a phenylboronate derivative undergoes a glucose‐dependent transition in its state of hydration under physiological conditions. The reversible surface‐localized dehydration enables the provision of insulin to be controlled, thus offering a new basis for the treatment of diabetes with long‐term stability and safety.

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