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Back Cover: Photoreversible Patterning of Biomolecules within Click‐Based Hydrogels (Angew. Chem. Int. Ed. 8/2012)
Author(s) -
DeForest Cole A.,
Anseth Kristi S.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201108165
Subject(s) - cover (algebra) , self healing hydrogels , biomolecule , nanotechnology , click chemistry , int , materials science , chemistry , polymer chemistry , engineering , computer science , mechanical engineering , operating system
Reversible biomolecular patterning in hydrogels can direct cell function in a user‐defined manner. In their Communication on page 1816 ff., K. S. Anseth and C. A DeForest report 4D spatiotemporal control over the presentation of bioligands by using a thiol–ene photoconjugation reaction, which is initiated by visible light, combined with the photocleavage of an o ‐nitrobenzyl ether, which is controlled by UV light. This method allows cell functions to be probed dynamically.