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Strong Metallophilic Interactions in the Palladium Arylation by Gold Aryls
Author(s) -
PérezTemprano Mónica H.,
Casares Juan A.,
de Lera Ángel R.,
Álvarez Rosana,
Espinet Pablo
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201108043
Subject(s) - palladium , aryl , chemistry , computer science , coupling (piping) , information retrieval , combinatorial chemistry , organic chemistry , materials science , catalysis , alkyl , metallurgy
It's the second step that counts : Arylation of Pd by Au takes place through transition states and intermediates featuring strong Au⋅⋅⋅Pd metallophilic interactions (see picture). However, the aryl transfer from [AuArL] to [PdArClL 2 ] is thermodynamically disfavored and will not occur unless an irreversible ArAr coupling from [PdAr 2 L 2 ] follows.