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Gold(I)‐Catalyzed Enantioselective Intramolecular Dehydrative Amination of Allylic Alcohols with Carbamates
Author(s) -
Mukherjee Paramita,
Widenhoefer Ross A.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201107877
Subject(s) - enantioselective synthesis , allylic rearrangement , amination , intramolecular force , yield (engineering) , catalysis , chemistry , organic chemistry , materials science , metallurgy
Aliphatic nitrogen heterocycles —either five‐ or six‐membered—are formed in high yield and with up to 94 % ee when a 1:2 mixture of [( S )‐ 2 ](AuCl) 2 and AgClO 4 is used as the catalyst for the title reaction.