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Enantioselective Iridium‐Catalyzed Hydrogenation of β,γ‐Unsaturated Carboxylic Acids: An Efficient Approach to Chiral 4‐Alkyl‐4‐aryl Butanoic Acids
Author(s) -
Song Song,
Zhu ShouFei,
Yang Shuang,
Li Shen,
Zhou QiLin
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201107802
Subject(s) - enantioselective synthesis , iridium , aryl , alkyl , catalysis , chemistry , organic chemistry , combinatorial chemistry
Chiral acids : A highly enantioselective iridium‐catalyzed hydrogenation of β,γ‐unsaturated carboxylic acids is developed for the preparation of chiral 4‐alkyl‐4‐aryl butanoic acids (see scheme).