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Self‐Powered Microscale Pumps Based on Analyte‐Initiated Depolymerization Reactions
Author(s) -
Zhang Hua,
Yeung Kimy,
Robbins Jessica S.,
Pavlick Ryan A.,
Wu Meng,
Liu Ran,
Sen Ayusman,
Phillips Scott T.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201107787
Subject(s) - microscale chemistry , depolymerization , analyte , polymer , monomer , chemistry , computer science , nanotechnology , polymer science , process engineering , combinatorial chemistry , chromatography , materials science , organic chemistry , engineering , mathematics , mathematics education
Pump it up : Insoluble polymer films that depolymerize to release soluble monomeric products when exposed to a specific analyte act as a microscale pump. Products formed as a result of depolymerization amplify the signal and create a concentration gradient that pumps fluids and insoluble particles away from the bulk polymer by a diffusiophoretic mechanism. These pumps can respond to a variety of analytes, from small molecules to enzymes.