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Ortho ‐Trifluoromethylation of Functionalized Aromatic Triazenes
Author(s) -
Hafner Andreas,
Bräse Stefan
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201107414
Subject(s) - trifluoromethylation , variety (cybernetics) , key (lock) , chemistry , computer science , transformation (genetics) , scheme (mathematics) , combinatorial chemistry , organic chemistry , mathematics , trifluoromethyl , artificial intelligence , biochemistry , alkyl , gene , mathematical analysis , computer security
A silver key to add CF 3 : In presence of in situ generated AgCF 3 , it is possible to trifluoromethylate aromatic triazenes in high ortho selectivity and good yields by means of a CH substitution (see scheme). Owing to the further transformation possibilities offered by triazenes, a variety of CF 3 ‐substituted building blocks are then accessible.