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A Trispyrazolylborato Iron Cysteinato Complex as a Functional Model for the Cysteine Dioxygenase
Author(s) -
Sallmann Madleen,
Siewert Inke,
Fohlmeister Lea,
Limberg Christian,
Knispel Christina
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201107345
Subject(s) - dioxygenase , cysteine , computer science , information retrieval , chemistry , biochemistry , gene , enzyme
The natural paragon taken seriously : A trispyrazolylborato cysteinato iron complex not only excellently mimics the active site structure of cysteine dioxygenase (see picture: both structures superimposed): a dioxygenation of cysteinate occurs on treatment with O 2 , and hence, the system represents the hitherto most realistic model for cysteine dioxygenase.