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Anchored Proteinase‐Targetable Optomagnetic Nanoprobes for Molecular Imaging of Invasive Cancer Cells
Author(s) -
Park Joseph,
Yang Jaemoon,
Lim EunKyung,
Kim Eunjung,
Choi Jihye,
Ryu Joo Kyung,
Kim Nam Hee,
Suh JinSuck,
Yook Jong In,
Huh YongMin,
Haam Seungjoo
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201106758
Subject(s) - biomarker , cancer cell , cancer , molecular biomarkers , cancer research , computational biology , nanotechnology , medicine , chemistry , biology , materials science , biochemistry
Activatable nanoprobe : A dual‐function nanoprobe has been developed that detects membrane type 1‐matrix metalloproteinase (MT1‐MMP) activity by a dual‐signal increase in complementary fluorescence imaging (FI) and magnetic resonance imaging (MRI). MNCs=magnetic nanocrystals, Q=quencher, F=fluorescence dye.