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Platinum‐Catalyzed Direct Amination of Allylic Alcohols with Aqueous Ammonia: Selective Synthesis of Primary Allylamines
Author(s) -
Das Kalpataru,
Shibuya Ryozo,
Nakahara Yasuhito,
Germain Nicolas,
Ohshima Takashi,
Mashima Kazushi
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201106737
Subject(s) - amination , phosphine , allylic rearrangement , chemistry , catalysis , organic chemistry , aqueous solution , ammonia , primary (astronomy) , combinatorial chemistry , physics , astronomy
Direct amination of unactivated allylic alcohols with aqueous ammonia was catalyzed by a Pt/phosphine complex to give the corresponding allylamines along with water as the sole by‐product. Under optimized reaction conditions, primary allylamines were obtained as major products with excellent monoallylation selectivity. cod=1,5‐cyclooctadiene.