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Unveiling the Shape of Aspirin in the Gas Phase
Author(s) -
Cabezas Carlos,
Alonso José L.,
López Juan C.,
Mata Santiago
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201106621
Subject(s) - aspirin , jet (fluid) , gas phase , supersonic speed , salicylic acid , rotational spectroscopy , microwave , fourier transform , spectroscopy , laser ablation , phase (matter) , laser , materials science , chemistry , analytical chemistry (journal) , optics , physics , chromatography , organic chemistry , mechanics , astronomy , biochemistry , quantum mechanics
Accurate structural information : The first high‐resolution study of isolated gas‐phase acetyl salicylic acid (aspirin) is reported. Solid aspirin was vaporized by laser ablation, expanded in a supersonic jet, and characterized by Fourier transform microwave spectroscopy (see picture). Two different neutral structures have been identified from the analysis of the rotational spectrum.