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Alkylboronic Esters from Copper‐Catalyzed Borylation of Primary and Secondary Alkyl Halides and Pseudohalides
Author(s) -
Yang ChuTing,
Zhang ZhenQi,
Tajuddin Hazmi,
Wu ChenCheng,
Liang Jun,
Liu JingHui,
Fu Yao,
Czyzewska Maria,
Steel Patrick G.,
Marder Todd B.,
Liu Lei
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201106299
Subject(s) - borylation , halide , reagent , alkyl , primary (astronomy) , chemistry , catalysis , copper , combinatorial chemistry , organic chemistry , functional group , polymer chemistry , aryl , physics , astronomy , polymer
Easy access : An unprecedented copper‐catalyzed cross‐coupling reaction of the title compounds with diboron reagents is described (see scheme; Ts=4‐toluenesulfonyl). This reaction can be used to prepare both primary and secondary alkylboronic esters having diverse structures and functional groups. The resulting products would be difficult to access by other means.