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Three‐Component [2+2+2] Cycloaddition of Carboryne, Unactivated Alkene, and Alkyne via Zirconacyclopentane Mediated by Nickel: One‐Pot Synthesis of Dihydrobenzocarboranes
Author(s) -
Ren Shikuo,
Qiu Zaozao,
Xie Zuowei
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201106212
Subject(s) - alkene , alkyne , cycloaddition , reactivity (psychology) , nickel , olefin fiber , component (thermodynamics) , chemistry , combinatorial chemistry , zirconium , database , computer science , organic chemistry , catalysis , physics , medicine , alternative medicine , pathology , thermodynamics
Mix three—get one : The complexation of a transition‐metal center to an olefin or alkyne can significantly modify its reactivity, which makes the selective coupling of different alkenes or alkynes to carboryne possible. An example of a three‐component [2+2+2] cycloaddition reaction of carboryne with unactivated alkene (see scheme, blue) and alkyne (red) mediated by zirconium and nickel complexes is described.