Photocontrollable Dynamic Micropatterning of Non‐adherent Mammalian Cells Using a Photocleavable Poly(ethylene glycol) Lipid | Zendy

Yamaguchi Satoshi | Zendy; Yamahira Shinya | Zendy; Kikuchi Kyoko | Zendy; Sumaru Kimio | Zendy; Kanamori Toshiyuki | Zendy; Nagamune Teruyuki | Zendy

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Photocontrollable Dynamic Micropatterning of Non‐adherent Mammalian Cells Using a Photocleavable Poly(ethylene glycol) Lipid

Author(s) -

Yamaguchi Satoshi,

Yamahira Shinya,

Kikuchi Kyoko,

Sumaru Kimio,

Kanamori Toshiyuki,

Nagamune Teruyuki

Publication year - 2012

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201106106

Subject(s) - ethylene glycol , peg ratio , micropatterning , substrate (aquarium) , linker , chemistry , biophysics , nanotechnology , combinatorial chemistry , materials science , computer science , biology , organic chemistry , operating system , finance , economics , ecology

Cells in the spotlight : A substrate was coated with a poly(ethylene glycol) (PEG) segment bound to a lipid through a linker that was cleaved by UV irradiation to leave a PEG‐coated area. Irradiation of an arbitrary pattern easily and rapidly yielded a high‐contrast cell pattern. Only the targeted cells on the cell pattern were selectively detached without cell damage on a microfluidic device (see picture).

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