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Graphene Oxide Nanoparticles as a Nonbleaching Optical Probe for Two‐Photon Luminescence Imaging and Cell Therapy
Author(s) -
Li JingLiang,
Bao HongChun,
Hou XueLiang,
Sun Lu,
Wang XunGai,
Gu Min
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201106102
Subject(s) - photothermal therapy , luminescence , graphene , materials science , femtosecond , irradiation , photon , laser , oxide , nanoparticle , optoelectronics , nanotechnology , optics , physics , nuclear physics , metallurgy
Lasting glow : Under femtosecond laser irradiation, graphene oxide nanoparticles (GONs) give strong two‐photon luminescence (TPL; see picture). The presence of GONs also induces microbubbling, which causes cell death at an order of magnitude lower laser power than when cells are not labeled. The results show that GONs can be used for TPL‐based imaging and photothermal cancer therapy.