Cross‐Coupling of Aryl Grignard Reagents with Aryl Iodides and Bromides through S RN 1 Pathway | Zendy

Shirakawa Eiji | Zendy; Hayashi Yumi | Zendy; Itoh Kenichi | Zendy; Watabe Ryo | Zendy; Uchiyama Nanase | Zendy; Konagaya Wataru | Zendy; Masui Seiji | Zendy; Hayashi Tamio | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Cross‐Coupling of Aryl Grignard Reagents with Aryl Iodides and Bromides through S RN 1 Pathway

Author(s) -

Shirakawa Eiji,

Hayashi Yumi,

Itoh Kenichi,

Watabe Ryo,

Uchiyama Nanase,

Konagaya Wataru,

Masui Seiji,

Hayashi Tamio

Publication year - 2012

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201106086

Subject(s) - aryl , tetrahydrofuran , reagent , chemistry , halide , toluene , grignard reagent , set (abstract data type) , solvent , combinatorial chemistry , grignard reaction , coupling (piping) , organic chemistry , computer science , materials science , programming language , alkyl , metallurgy

Game, SET, and match : Aryl Grignard reagents undergo coupling with aryl halides when toluene is used as a solvent in combination with a small amount of tetrahydrofuran (see scheme). The reaction proceeds through an S RN 1 mechanism, and does not require any transition metal catalysts.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research