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The Art of Fluorescence Imaging with Chemical Sensors
Author(s) -
Schäferling Michael
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201105459
Subject(s) - fluorescence , nanotechnology , fluorescence lifetime imaging microscopy , computer science , focus (optics) , visualization , optical imaging , signal (programming language) , imaging science , chemical sensor , data science , materials science , artificial intelligence , chemistry , optics , physics , electrode , programming language
Fluorescence imaging techniques involving chemical sensors are essential tools in many fields of science and technology because they enable the visualization of parameters which exhibit no intrinsic color or fluorescence, for example, oxygen, pH value, CO 2 , H 2 O 2 , Ca 2+ , or temperature, to name just a few. This Review aims to highlight the state of the art of fluorescence sensing and imaging, starting from a comprehensive overview of the basic functional principles of fluorescent probes (or indicators) and the design of sensor materials. The focus is directed towards the progress made in the development of multiple sensors and methods for their signal read out. Imaging methods involving optical sensors are applied in quite diverse scientific areas, such as medical research, aerodynamics, and marine research.