On the Nature of CH⋅⋅⋅FC Interactions in Hindered CF 3 C(sp 3 ) Bond Rotations | Zendy

Prakash G. K. Surya | Zendy; Wang Fang | Zendy; Rahm Martin | Zendy; Shen Jingguo | Zendy; Ni Chuanfa | Zendy; Haiges Ralf | Zendy; Olah George A. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

On the Nature of CH⋅⋅⋅FC Interactions in Hindered CF 3 C(sp 3 ) Bond Rotations

Author(s) -

Prakash G. K. Surya,

Wang Fang,

Rahm Martin,

Shen Jingguo,

Ni Chuanfa,

Haiges Ralf,

Olah George A.

Publication year - 2011

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201105288

Subject(s) - non covalent interactions , hydrogen bond , quantum chemical , cinchona , character (mathematics) , chemistry , content (measure theory) , computational chemistry , organic chemistry , mathematics , molecule , catalysis , mathematical analysis , geometry , enantioselective synthesis

In cinchona alkaloid‐based scaffolds , hindered CF 3 rotations have been observed. The variation in barrier heights for the CF 3 rotations is controlled by the corresponding entropic changes when the substituents are changed from an allyl to a bulky 9‐methylanthracenyl group. Quantum chemical and experimental studies have shown that the noncovalent C3′H1⋅⋅⋅FC interactions in the studied cases possess a weak hydrogen bonding‐like character.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research