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Active‐Metal Template Synthesis of a Molecular Trefoil Knot
Author(s) -
Barran Perdita E.,
Cole Harriet L.,
Goldup Stephen M.,
Leigh David A.,
McGonigal Paul R.,
Symes Mark D.,
Wu Jhenyi,
Zengerle Michael
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201105012
Subject(s) - trefoil knot , template , trefoil , knot (papermaking) , chemistry , computer science , tying , combinatorial chemistry , click chemistry , stereochemistry , programming language , engineering , biology , operating system , chemical engineering , agronomy , knot theory
Tying the knot : The marriage of catalysis and coordination chemistry enables two Cu I ions (red; see picture) to work in partnership for the synthesis of a molecular trefoil knot. One ion entangles an acyclic building block to create a loop in the ligand, and the other gathers the ligand's reactive end‐groups, threads the loop, and catalyzes the covalent capture of the knotted architecture by an alkyne–azide “click” reaction.