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Asymmetric α Alkylation of Aldehydes: Efficiency with Elegance
Author(s) -
TakTak Lotfi,
Dhimane Hamid,
Dalko Peter I.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201105001
Subject(s) - elegance , alkylation , intermolecular force , chemistry , computational chemistry , combinatorial chemistry , organic chemistry , molecule , catalysis , aesthetics , philosophy
Simple and practical : Direct intermolecular α alkylation reactions by S N 1‐type transformations have been developed and offer flexible and robust routes to major compound classes, for which the direct preparations were unavailable before.