Premium
Ditopic Ion Transport Systems: Anion–π Interactions and Halogen Bonds at Work
Author(s) -
Vargas Jentzsch Andreas,
Emery Daniel,
Mareda Jiri,
Metrangolo Pierangelo,
Resnati Giuseppe,
Matile Stefan
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201104966
Subject(s) - counterion , halogen , halogen bond , ion , chemistry , organic cation transport proteins , atom (system on chip) , chemical physics , computational chemistry , combinatorial chemistry , transporter , computer science , organic chemistry , biochemistry , alkyl , gene , embedded system
Single‐atom exchange series are introduced to extract the individual contributions of halogen bonds and anion–π interactions to the transport of anions across lipid bilayer membranes (see picture). Known cation binding sites are used for counterion activation of the neutral calix[4]arene transporters. The experimental evidence for anion transport with halogen bonds is unprecedented.