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Back Cover: Stereospecific Palladium‐Catalyzed Decarboxylative C(sp 3 )C(sp 2 ) Coupling of 2,5‐Cyclohexadiene‐1‐carboxylic Acid Derivatives with Aryl Iodides (Angew. Chem. Int. Ed. 37/2011)
Author(s) -
Chou ChihMing,
Chatterjee Indranil,
Studer Armido
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201104737
Subject(s) - stereospecificity , decarboxylation , aryl , palladium , chemistry , carboxylic acid , stereoselectivity , catalysis , medicinal chemistry , alkyl , stereochemistry , organic chemistry
Decarboxylation of aryl, allyl, and alkyl metal carboxylates, which are readily accessible from carboxylic acids, offers an attractive approach for the generation of the corresponding organometallic compounds. In their Communication on page 8614 ff., A. Studer and co‐workers report on highly stereospecific decarboxylative palladations of 2,5‐cyclohexadiene‐1‐carboxylic acids. Stereoselective arylation of these intermediates delivers optically active arylated cyclohexadienes.