X‐Ray Computed Tomography Imaging of Breast Cancer by using Targeted Peptide‐Labeled Bismuth Sulfide Nanoparticles | Zendy

Kinsella Joseph M. | Zendy; Jimenez Rebecca E. | Zendy; Karmali Priya P. | Zendy; Rush Anthony M. | Zendy; Kotamraju V. Ramana | Zendy; Gianneschi Nathan C. | Zendy; Ruoslahti Erkki | Zendy; Stupack Dwayne | Zendy; Sailor Michael J. | Zendy

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X‐Ray Computed Tomography Imaging of Breast Cancer by using Targeted Peptide‐Labeled Bismuth Sulfide Nanoparticles

Author(s) -

Kinsella Joseph M.,

Jimenez Rebecca E.,

Karmali Priya P.,

Rush Anthony M.,

Kotamraju V. Ramana,

Gianneschi Nathan C.,

Ruoslahti Erkki,

Stupack Dwayne,

Sailor Michael J.

Publication year - 2011

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201104507

Subject(s) - nanoparticle , peptide , computed tomography , breast cancer , bismuth , cancer imaging , computed tomography laser mammography , tomography , cancer , x ray , materials science , sulfide , chemistry , nuclear medicine , nanotechnology , preclinical imaging , medicine , radiology , optics , biochemistry , in vivo , organic chemistry , physics , microbiology and biotechnology , biology

Enhanced visualization of breast cancer in X‐ray computed tomography was achieved by using Bi 2 S 3 nanoparticles of 10 nm diameter modified to display a tumor targeting peptide (LyP‐1, CGNKRTRGC). Accumulation within the tumor was increased by 260 % over non‐labeled nanoparticles.

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