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Iridium‐Catalyzed Reactions of ω‐Arylalkanols to α,ω‐Diarylalkanes
Author(s) -
Obora Yasushi,
Anno Yuka,
Okamoto Ryuhei,
Matsuura Toyomi,
Ishii Yasutaka
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201104452
Subject(s) - dehydrogenation , decarbonylation , catalysis , iridium , alkyl , alkylation , chemistry , combinatorial chemistry , organic chemistry
The long and the short of it : An atom‐economical route to α,ω‐diarylalkanes from ω‐arylalkanols was achieved by a direct one‐step method, or a sequential two‐step method depending on the alkyl chain length. The reaction proceeded through the formation of β‐methylhydroxy‐α,ω‐diarylalkanes by dehydrogenation/β‐alkylation, followed by dehydrogenation/decarbonylation.