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Induced Nanoelectrospray Ionization for Matrix‐Tolerant and High‐Throughput Mass Spectrometry
Author(s) -
Huang Guangming,
Li Guangtao,
Cooks R. Graham
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201103687
No‐contact rule : The title method is ultra‐sensitive, high‐throughput (4 samples per second), easily multiplexed, and is compatible with serum, urine, and concentrated salt solutions. Other features of this method, which avoids physical contact between the electrode and the solvent (see picture), include sample economy and the ability to produce both positive and negative‐ion spectra in one cycle.