Premium
Cobalt‐Catalyzed 1,4‐Hydrobutadienylation of 1‐Aryl‐1,3‐dienes with 2,3‐Dimethyl‐1,3‐butadiene
Author(s) -
Bohn Martin A.,
Schmidt Anastasia,
Hilt Gerhard,
Dindaroğlu Mehmet,
Schmalz HansGünther
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201103613
Subject(s) - 1,3 butadiene , cobalt , chemoselectivity , catalysis , diene , aryl , yield (engineering) , olefin fiber , ligand (biochemistry) , chemistry , medicinal chemistry , organic chemistry , materials science , alkyl , receptor , biochemistry , natural rubber , metallurgy
Round and round the olefin goes! A cobalt‐catalyzed 1,4‐hydrobutadienylation of a 1‐aryl‐substituted 1,3‐diene with 2,3‐dimethyl‐1,3‐butadiene yields 1,3,6‐triene derivatives in excellent yield and chemoselectivity. The application of a bulky ligand (SchmalzPhos) leads to the selective formation of a single regio‐ and stereoisomer.