Computationally Guided Stereocontrol of the Combined CH Functionalization/Cope Rearrangement | Zendy

Lian Yajing | Zendy; Hardcastle Kenneth I. | Zendy; Davies Huw M. L. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Computationally Guided Stereocontrol of the Combined CH Functionalization/Cope Rearrangement

Author(s) -

Lian Yajing,

Hardcastle Kenneth I.,

Davies Huw M. L.

Publication year - 2011

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201103568

Subject(s) - surface modification , state (computer science) , transition (genetics) , chemistry , computer science , combinatorial chemistry , algorithm , biochemistry , gene

Diastereoselectivity in control : The synthetic utility of the CH functionalization/Cope rearrangement reaction has been greatly expanded by the design of substrates that will react through a boat transition state instead of a chair transition state. The products are formed with the opposite diastereoselectivity as previously obtained (see scheme, ABSA= acetamidobenzenesulfonylazide).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research